Genome stability in embryonic development and reprogramming

Abstract: The events occurring in the beginning of human development are highly consequential for everything that follows, but remain poorly understood and little investigated. Most human embryos fail to develop shortly after fertilization. This inefficiency in development is primarily caused by an unstable genome, resulting in aneuploidies, DNA damage, cell cycle arrest, and in developing embryos likely novel mutations. I will present our novel insight on how the embryo replicates its DNA and how inefficiencies in DNA repair in the embryo shape fertility as well as our health throughout life.

biochemistrycancer biologychemical biologycell biologydevelopmental biologydrug discoveryevolutiongeneticsimmunologymolecular biologymicrobiologyneuroscienceplant sciencessystems biologybiotechnologybiological techniquesbiophysics

Audience: researchers in the discipline

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Colloquium zooming Molecular & Cellular Biology LUMS

Series comments: Zooming Molecular & Cellular Biology Colloquium was initiated on July 28th, 2020 by the Biology department at Syed Babar Ali School of Science & Engineering (SBASSE), Lahore University of Management Sciences (LUMS). The series follows through various topics which come under the ambit of Molecular and Cellular Biology and we’ve had the pleasure and honor of hosting some of the most knowledgeable scientists from around the globe. Organizers can be reached out at 24100162@lums.edu.pk or 24100001@lums.edu.pk for the Zoom link of individual talks. All lectures are LIVE streamed on SBASSE's official Facebook page.